Networks, epidemics and vaccination through contact tracing.
نویسندگان
چکیده
We consider a (social) network whose structure can be represented by a simple random graph having a pre-specified degree distribution. A Markovian susceptible-infectious-removed (SIR) epidemic model is defined on such a social graph. We then consider two real-time vaccination models for contact tracing during the early stages of an epidemic outbreak. The first model considers vaccination of each friend of an infectious individual (once identified) independently with probability p. The second model is related to the first model but also sets a bound on the maximum number an infectious individual can infect before being identified. Expressions are derived for the influence on the reproduction number of these vaccination models. We give some numerical examples and simulation results based on the Poisson and heavy-tail degree distributions where it is shown that the second vaccination model has a bigger advantage compared to the first model for the heavy-tail degree distribution.
منابع مشابه
Effect of Small-World Networks on Epidemic Propagation and Intervention
The small-world network, characterized by special structural properties of high connectivity and clustering, is one of the highlights in recent advances in network science and has the potential to model a variety of social contact networks. In an attempt to better understand how these structural properties of small-world networks affect epidemic propagation and intervention, this article uses a...
متن کاملContact tracing and epidemics control in social networks.
A generalization of the standard susceptible-infectious-removed stochastic model for epidemics in sparse random networks is introduced which incorporates contact tracing in addition to random screening. We propose a deterministic mean-field description that yields quantitative agreement with stochastic simulations on random graphs. Both the stochastic simulations and the mean-field equations sh...
متن کاملThe effect of network mixing patterns on epidemic dynamics and the efficacy of disease contact tracing
In networks, nodes may preferentially contact other nodes with similar (assortatively mixed) or dissimilar (disassortatively mixed) numbers of contacts. Different patterns of contact support different epidemic dynamics, potentially affecting the efficacy of control measures such as contact tracing, which aims to identify and isolate nodes with infectious contacts. We used stochastic simulations...
متن کاملThe role of vaccination in the control of sars.
We assess pre-outbreak and during-outbreak vaccination as control strategies for SARS epidemics using a mathematical model that includes susceptible, latent (traced and untraced), infectious, isolated and recovered individuals. Scenarios focusing on policies that include contact tracing and levels of self-isolation among untraced infected individuals are explored. Bounds on the proportion of pr...
متن کاملEpidemic prediction and control in weighted networks.
Contact networks are often used in epidemiological studies to describe the patterns of interactions within a population. Often, such networks merely indicate which individuals interact, without giving any indication of the strength or intensity of interactions. Here, we use weighted networks, in which every connection has an associated weight, to explore the influence of heterogeneous contact s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Mathematical biosciences
دوره 216 1 شماره
صفحات -
تاریخ انتشار 2008